Bone formation appears to be controlled by serotonin, a chemical that had been known mainly for its entirely separate role in the brain, researchers are reporting. The discovery could have enormous ...

A recent study identifies Neural EGFL-like 2 (NELL2), a secreted protein, as a key regulator of bone homeostasis, offering potential therapeutic applications for osteoporosis. NELL2 promotes ...

Basic, translational and clinical research over the past few decades has provided new understanding on the mechanisms by which activation of the receptor of parathyroid hormone (parathyroid hormone 1 ...

A recent study identifies Neural EGFL-like 2 (NELL2), a secreted protein, as a key regulator of bone homeostasis, offering potential therapeutic applications for osteoporosis. NELL2 promotes ...

Skeletal bone is maintained by bone remodeling, in which old and damaged bone is replaced with new bone through continuous cellular processes that are mainly controlled by bone-resorbing osteoclasts ...