Homologous recombination (HR) is central to the template-based repair of DNA double-strand breaks, maintaining genome integrity 1,2,3,4. A central reaction in HR is the strand exchange, in which the ...

DNA2 is implicated in DNA repair and replication 12. A prevailing model posits that a role in Okazaki fragment processing during lagging-strand replication renders DNA2 essential for cell ...

Every day, billions of cells in your body divide, helping to replace old and injured cells with new ones. And each time this happens, your entire genetic library—your genome, which totals more than 3 ...

It’s tricky to make an exact copy of yourself. Or at least it is for cells undergoing mitosis, where cells replicate everything inside of them, including their neatly packaged DNA, then split in half.