Model for ORF1p-RNP formation and DNA recognition. ORF1p forms homo trimers and higher-order oligomers that can bind to DNA but have a clear preference for RNA. Credit: Sarah Zernia et al Model for ...

DNA does not float freely in the cell. Instead, it is wrapped around histone proteins to form structures called nucleosomes.

Our DNA is constantly being packed and unpacked. And there is a good reason for this: depending on its packing state, it performs different functions in the cell nucleus. For most of its life – this ...

For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how ...

If DNA bridges remain between chromosomes after cell division, chromosome segregation can be disrupted, leading to genetic instability and increasing the risk of cancer. Researchers at UNIST and the ...

If measured from beginning to end, the DNA in our cells is too long to fit into the cell’s nucleus, explaining why it must be constantly folded and packaged. When it is time for cell division, and the ...

Researchers at The University of Hong Kong (HKU) have made an exciting discovery about how human cells protect DNA during cell division, offering new insights into combating diseases such as cancer.

Processes such as wound healing, hair growth, and the continual renewal of cells all rely on cell division. In this process, chromosomes must be evenly distributed between two daughter cells. Even ...

(Nanowerk News) If measured from beginning to end, the DNA in our cells is too long to fit into the cell’s nucleus, explaining why it must be constantly folded and packaged. When it is time for cell ...