Scientists from Skoltech and the University of Potsdam have developed a physical theory that sheds light on how molecular ...
Not all DNA looks like the familiar double helix. Sometimes, parts of our genetic code fold into unusual shapes under certain conditions. One such structure known as a G-quadruplex (G4) looks like a ...
Thought LeadersMaxim Molodtsov, Ph.D. Randhir Kumar, Ph.D. From optical trapping experiments to insights into molecular force generation, Dr. Maxim Molodtsov shared how his research is uncovering the ...
The illustration shows DNA being folded into a loop by an SMC motor called cohesin (in purple/blue). The purple part of the motor (with a red/green label) is the protein subunit NIPBL, which acts as a ...
An asymmetric kleisin path breaks the symmetry of the SMC homodimer, ensuring unidirectional DNA translocation via a segment capture mechanism.
For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how ...
Scientists from Delft, Vienna, and Lausanne discovered that the protein machines that shape our DNA can switch direction. Until now, researchers believed that these so-called SMC motors that make ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results