The first crystal structure of an alternative DNA shape from the insulin gene has been revealed. The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a ...

A team led by Professor Michal Hocek at IOCB Prague has explored the limits of the structure and function of DNA and successfully pushed forward known boundaries. Their latest research has just been ...

“We’re only just beginning to understand the full majesty of life on Earth,” wrote the founding members of the Earth BioGenome Project in 2018. The ambitious project raised eyebrows when first ...

Understanding the mechanisms of protein-DNA binding is critical in comprehending gene regulation. Three-dimensional DNA structure, also described as DNA shape, plays a key role in these mechanisms. In ...

(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.) Gabrielle Hartley, University of Connecticut (THE CONVERSATION) When the Human Genome ...

PARP1 detection of DNA strand breaks allosterically leads to PARP1 synthesis of poly(ADP-ribose) modifications that signal DNA damage. HPF1 engages activated PARP1 to control modification site ...

An international collaborative research team has discovered that G-quadraplex DNA (G4-DNA) accumulates in neurons and dynamically controls the activation and repression of genes underlying long-term ...

Every year on the 25th of April, the world celebrates National DNA Day; an awareness day celebrating the discovery of the DNA double helix. This year however, commemorates the 70th anniversary of the ...

Monday, 21 October: Maynooth University computer scientist Professor Damien Woods has been awarded €4 million in funding under the European Innovation Council Pathfinder Challenge programme, with his ...

In the double helix structure of DNA, thymine forms a base pair with adenine through two hydrogen bonds. This specific pairing is known as complementary base pairing and is essential for the stability ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...