Sox9, a master regulator of cartilage formation, switches its target genes dynamically during embryonic limb development instead of following a fixed program, as reported by researchers from Science ...

Scientists at the Leibniz Institute on Aging—Fritz Lipmann Institute (FLI) in Jena have discovered a previously unknown function of immune cells in the bone marrow. Embryonic macrophages—specialized ...

Mechanotransduction—the process by which cells convert mechanical forces into biochemical signals—is now recognised as a fundamental regulator of embryonic morphogenesis. During early development, ...

Camille Berthelot is in the Department of Genomes and Genetics, the Pasteur Institute, Paris Cité University, CNRS UMR 3525, INSERM UA12, F-75015 Paris, France. Using an exceptionally rare collection ...

SSCs are essential for bone development, homeostasis, and repair. Recent studies have identified distinct SSC populations in long bones, craniofacial bones, and spine. Techniques like single-cell ...