An international team of scientists led from Sweden's Karolinska Institutet has for the first time mapped all the genes that are activated in the first few days of a fertilized human egg. The study, ...

The placenta is a vital organ for fetal development, providing structural support and mediating both nutrient exchange and maternal–fetal immune interactions. However, there are many aspects of murine ...

During early embryonic development in mammals, the totipotency of the zygote — which is reprogrammed from the differentiated gametes — transitions to pluripotency by the blastocyst stage, coincident ...

Over the past few decades, growing evidence has challenged the belief that inheritance is governed solely by DNA sequences. Scientists now recognise the crucial role of epigenetic inheritance – the ...

A new study reveals that age-related autophagy decline blocks embryo development by triggering a lipid-burning crisis.

In the earliest hours after fertilization, an embryo takes its first steps toward becoming a living organism by shedding maternal control and activating its own genetic program. This critical process, ...

Bioengineering researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed a soft, thin, stretchable bioelectronic device that can be implanted into a ...

Sox9, a master regulator of cartilage formation, switches its target genes dynamically during embryonic limb development instead of following a fixed program, as reported by researchers from Science ...

Cell division is an essential process for all life on earth, yet the exact mechanisms by which cells divide during early embryonic development have remained elusive – particularly for egg-laying ...

Glycolysis is an ancient metabolic activity. It consists of a set of reactions that convert glucose into energy. This central process allows cells to grow, divide, and stay alive. It has accompanied ...

Eating large amounts of ultra-processed food (UPF) is linked not only to reduced fertility in men, but also to slower growth in early embryos, and smaller yolk sacs, which are essential for early ...