Researchers at the University of Tsukuba have developed a vector that integrates the Cre enzyme gene with the specific DNA sequence loxP, which is its target. This vector allows the creation of ...

Cellular RNAs are extensively decorated with chemical modifications that fine-tune gene expression at multiple levels. Among these, N6-methyladenosine (m6A) emerges as the most abundant internal mark ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

Emerging gene editing platforms are revolutionizing precision medicine, enabling safe and effective genetic modifications for ...

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it ...

Sodium Hydrogen Exchangers (NHEs) are a family of proteins that utilize the electrochemical gradient of Na+ influx to export intracellular H+ ions1. Sodium Hydrogen Exchangers (NHEs) are a family of ...

Mice and newts were applied to the one-step Cre-loxP organism creation technology by TAx9. In this study, the researchers succeeded in synthesizing a Cre-loxP integrated vector by placing a short DNA ...