At the turn of the century, the biomedical research community saw a landmark global effort, when scientists built a reference human genome sequence to better understand the genes underlying health and ...

T cells are essential components of the immune system and play critical roles in immune responses against infections, tumors, and autoimmune diseases. T cells are highly heterogeneous, with distinct ...

A research team led by Professor Simona Giunta at the University of Rome La Sapienza has produced the first reference-quality genome assembly of an experimentally relevant human cell line, the widely ...

Researchers have used a new human reference genome, which includes many duplicated and repeat sequences left out of the original human genome draft, to identify genes that make the human brain ...

UC Santa Cruz has a long history of pioneering advances in genomics research. The first working draft of a human genome sequence was assembled on our campus in 2000, which has led to enormous leaps in ...

Due to their repetitive and complex DNA sequences, centromeres have been viewed as the "black boxes" of the genome for decades. Often overlooked in sequencing projects but playing a critical role in ...

Data from a new study links a pair of duplicated genes to human brain features. The research provides a roadmap for scientists to gain a deeper understanding of brain function and evolution, as well ...

Finding chemicals in bodily fluids is evidence of contact with them through inhalation, dermal exposure, or ingestion, and it typically leads to two questions that pose important challenges in ...