Stay ahead in the rapidly evolving LNP space with the 4 th LNP Formulation & Process Development Summit - the largest global meeting dedicated purely to LNPs. The official event guide is your ...
AI-Designed Dual ATR-mTOR Inhibitor Demonstrates In Vivo Efficacy; Novel LNP Formulation of Bifunctional PARP/HDAC Inhibitor kt-3283 Successfully Characterized VANCOUVER, British Columbia, April 22, ...
Once the most successful mRNA-based LNP was tested in 3D in vitro models, the fluorescent dye continued to facilitate monitoring of LNP transfection and eGFP expression. This testing identified the ...
– Novel lipid nanoparticles entirely built on the POZ Platform that overcome the PEG immunogenicity dilemma – Design & synthesis of novel ionizable POZ lipids to replace current ionizable lipids for ...
From vaccines to personalized cancer therapies, scientists are studying the use of mRNA across many clinical applications. However, there are several factors that are unique to mRNA drug product ...
AI has designed candidate drugs for antibiotic-resistant infections and genetic diseases. But efforts to incorporate AI into the design of lipid nanoparticles (LNPs), the revolutionary delivery ...
Engineers have developed an automated microfluidic platform that dramatically accelerates the formulation of lipid nanoparticles, the delivery vehicles behind mRNA vaccines and gene therapies.
Fig. 2 Examples of ionizable lipids, sterols, phospholipids, and PEG-lipids used in LNP formulations. Created with BioRender.com. Fig. 3 High-throughput screening of the 3-component ionizable ...
– Design & synthesis of novel ionizable POZ lipids to replace current ionizable lipids for the delivery of a multitude of oligonucleotide payloads – Entitled "Novel Lipid Nanoparticles Built Entirely ...
– Design & synthesis of novel ionizable POZ lipids to replace current ionizable lipids for the delivery of a multitude of oligonucleotide payloads – HUNTSVILLE, AL, April 07, 2026 (GLOBE NEWSWIRE) ...