In a recent study published in Nature Communications, researchers performed genome-wide copy number profiling of the androgen receptor (AR) on metastases from deceased prostate cancer patients. Study: ...
Various approaches have been developed to identify and quantitate copy-number variation. A new, high-resolution approach that already shows promise is digital PCR. As illustrated by many research ...
Changes in genomic copy number can also occur via whole-genome doubling (WGD) and chromothripsis. These evolutionary events may be rampant during tumor development and can transpire into the evolution ...
The evolution of the MUC7 gene, which encodes a saliva protein, was studied by scientists at the University at Buffalo. To capture the gene’s proline-, threonine-, and serine-rich tandem repeat copy ...
We learn that we inherit two copies of every gene, one from each of our parents, but the story is a bit more complex. Some parts of the genome may be duplicated, or deleted, in some people. The number ...
Comprehensive targeted next-generation sequencing to reveal limited clonal evolution after concurrent chemoradiation in patients with squamous cell carcinoma of the head and neck. This is an ASCO ...
Association of Timely Comprehensive Genomic Profiling With Precision Oncology Treatment Use and Patient Outcomes in Advanced Non–Small-Cell Lung Cancer Somatic chromosomal alterations, particularly ...
Early treatment in SMA provides benefits, but children with two SMN2 copies may still experience significant motor delays and disabilities. Infants with two SMN2 copies showed delayed motor milestones ...
Understanding the relationship between mtDNA and animal growth could provide valuable information for selective breeding in aquaculture. However, the complex interactions between genetics and ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results