How does the placebo effect work? A new study identifies the vlPAG brain region and endogenous opioid signaling as the keys to expectancy-driven pain relief.

This article examines emerging non-opioid strategies for chronic pain, from targeted ion-channel drugs and anti-inflammatory ...

Staying physically active improves pain modulation and reduces the risk of older adults developing chronic pain, according to new research by Kelly Naugle and colleagues at Indiana University-Purdue ...

NEW IBS research highlights persistent pain treatment gaps and points to peripheral nerve targets for future, safer therapies ...

A noninvasive, home-based brain treatment with transcranial direct current stimulation (tDCS) can reduce pain severity, improve pain-related disability, and enhance endogenous pain modulation in women ...

The need to recognize and manage chronic nociplastic pain has become integral to rheumatology practice, as research over the past half-decade has affirmed that when central sensitization is present, ...

51.6 million Americans live with chronic pain. A new device created by USC biomedical engineers could help sufferers avoid the need for opioids. Image/Karolina Grabowska, Pexels. Chronic pain is a ...

Expert ideas for treating chronic pain. Source: PublicDomainPictures / Pixabay In this era of the opioid epidemic, it’s evermore important to find effective tools for treating chronic pain. These 10 ...