Proteins are how cells get work done. They carry out nearly every important cellular task, from ferrying messages to ...

Scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) report that inactivating a certain protein-coding gene promotes liver tissue regeneration in mammals. "This ...

Researchers reveal the fundamental role that mRNA’s tail, the 3′UTR, plays in the folding of complex regulatory proteins. Proteins are how cells get work done. They carry out nearly every important ...

Genome-wide association studies (GWAS) have identified multiple loci associated with complex diseases, but these are mostly ...

Late in 2025, we covered the development of an AI system called Evo that was trained on massive numbers of bacterial genomes. So many that, when prompted with sequences from a cluster of related genes ...

Like islands scattered across a vast intergenic sea, the nearly 20,000 protein-coding genes within the human genome represent a mere 2 percent of its 3 billion base pairs. When, where, and to what ...

Overview of protein engineering strategies. Directed evolution mimics natural selection in the laboratory through iterative rounds of mutagenesis and screening. Rational design uses structural and ...