Powerful single-molecule approaches have been developed for the accurate measurement of protein oligomers, but they are often low throughput and limited to the measurement of specific systems. To ...

Structure-based virtual screening approaches like molecular docking rely on accurately identifying and precisely calculating binding pockets to efficiently search for potential ligands. In this paper, ...

Protein detection sensitivity has historically lagged behind nucleic acid detection by 2-3 orders of magnitude due to the lack of intrinsic signal amplification. While digital methods such as Single ...