Structured illumination microscopy (SIM) is the most preferable system for live-cell super-resolution imaging. It enables the observation of intricate subcellular dynamics. However, conventional SIM ...

Super-resolution optical microscopy (SRM) is capable of surpassing the optical diffraction limit and can achieve spatial resolutions well below 200 nm 1. In the life sciences, this enables the ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

Super-resolution fluorescence microscopy has transformed our ability to visualise biological structures at the nanoscale by breaking the classical diffraction barrier of light. Traditional optical ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

Dual-color live-cell super-resolution imaging of mitochondria (green) and endoplasmic reticulum (magenta). Compared to the standard SN2N method, the proposed Adaptive-SN2N (aSN2N) framework ...

Using a tiny, spherical glass lens sandwiched between two brass plates, the 17th-century Dutch microscopist Antonie van Leeuwenhoek was the first to officially describe red blood cells and sperm cells ...

SAN DIEGO & OXFORD, England--(BUSINESS WIRE)--ONI (Oxford Nanoimaging), a life science tools company focused on developing super-resolution microscopy, announced today the launch of the Aplo Scope, a ...

Overcoming the resolution limit in a light microscope of around half a wavelength of light (about 250 nanometers) is one of the most significant developments in optics. Due to the wave nature of light ...

Peking University, Aug 18, 2025: Professor Xi Peng’s team from the College of Future Technology at Peking University has recently developed a triangle structured illumination microscopy (SIM), which ...