Single-cell sequencing is useful for a number of applications. For example, it can reveal cellular heterogeneity inside complex tissues, such as tumors. It can also provide information about how ...
Multiplex gene-editing is gaining popularity due to the flexibility and safety provided by double-strand break-independent base and prime editing technologies, but assays to accurately quantify ...
A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...
As single-cell genomics experiments grow in size, so too does the need for sequencing. Several large projects have recently called on the relative newcomer to the NGS scene, Ultima Genomics, for their ...
Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...