Hierarchical spatial organization is ubiquitous in tissue and organ biology. Systematic, high-dimensional phenotypic measurements of this organization, generated through experimental tools such as ...

Many physiological processes rely on cellular communication through ligand mediated signalling, where ligands secreted by cells diffuse through the extracellular space and bind to receptors to trigger ...

Spatial transcriptomics is a technique that provides information about gene expression patterns within intact tissues. This technology employs various methodologies, including in situ sequencing (ISS) ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...