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med's go on Instagram: "Hereditary spherocytosis is characterized by membrane protein defects (most commonly spectrin or ankyrin) that cause loss of red blood cell membrane surface area without loss of hemoglobin. This results in smaller, denser spherocytes with a decreased surface area-to-volume ratio, leading to an increased mean corpuscular hemoglobin concentration (MCHC), a relatively unique finding among anemias. Reticulocytosis and hemolysis are present, but MCV is often normal or slightly
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med's go on Instagram: "Hereditary spherocytosis is characterized by membrane protein defects (most commonly spectrin or ankyrin) that cause loss of red blood cell membrane surface area without loss of hemoglobin. This results in smaller, denser spherocytes with a decreased surface area-to-volume ratio, leading to an increased mean corpuscular hemoglobin concentration (MCHC), a relatively unique finding among anemias. Reticulocytosis and hemolysis are present, but MCV is often normal or slightly
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